منابع مشابه
The microRNA spectrum in 12 body fluids.
BACKGROUND MicroRNAs (miRNAs) are small, noncoding RNAs that play an important role in regulating various biological processes through their interaction with cellular messenger RNAs. Extracellular miRNAs in serum, plasma, saliva, and urine have recently been shown to be associated with various pathological conditions including cancer. METHODS With the goal of assessing the distribution of miR...
متن کاملmicroRNA biomarkers in body fluids of prostate cancer patients.
The abundance of miRNAs - small non-coding RNAs involved in posttranscriptional regulation of gene expression - in tissues and body fluids of cancer patients hold great promise to identify specific biomarkers, which may be useful for early diagnosis as well as to predict the clinical outcome and treatment response. For the extraction and quantification of miRNAs from cells and tissues, present ...
متن کاملThe origin, function and diagnostic potential of extracellular microRNA in human body fluids
Over the past several years extracellular microRNAs (miRNAs) have been found in all mammalian body fluids such as blood plasma, saliva, urine, milk, seminal plasma, tears, and amniotic fluid as circulating entities capable of predicting the course of a wide range of diseases. Great progress has been made so far in understanding their existence. However, the mechanism of generation and the biolo...
متن کاملAcetylsulfisoxazole in Body Fluids
We describe a simple, rapid chromatographic method for separating and quantitatively determining sulfisoxazole and its N4-acetyl metabolite in plasma and urine. A 100-zL sample of plasma or urine is combined with 200 tL of a solution containing 12 mg/L of the internal standard, Nt acetylsulfamethoxazole, in absolute methanol and centrifuged to obtain a clear supernatant solution. This solution ...
متن کاملBody Fluids
When thinking about fluid within the body we are essentially thinking about water. Tight regulation of the balance between water intake and output, and its distribution, is vital to the optimal function of every organ system within the body. In a wide variety of illnesses and during surgery, disturbances to this fine balance occur which must be identified and corrected to prevent deterioration,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2010
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2010.147405